Molecular determinants of HCO3- and cation transport in the human cation-dependent Cl-/HCO3- exchanger AE4

By sjmartinez • May 7, 2025

Catalán MA, Flores-Aldama L, Fernández F, Bustos D, Apablaza N, Hidalgo A, Mazola Y, Matamala E, Kao LY, Kurtz I, Spichiger C, Sarmiento J, Brauchi S, González W, Zúñiga L, Peña-Münzenmayer G. Molecular determinants of HCO₃^- and cation transport in the human cation-dependent Cl^-/HCO₃^-exchanger AE4. Am J Physiol Cell Physiol. 2025 May 6. doi: 10.1152/ajpcell.00346.2024. Epub ahead of print. PMID: 40327716.

Tags: aminoacidic residues, Cl-/cation-HCO3- exchanger, ion binding site, molecular dynamics, Nephrology, Publications, transport mechanism

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