De novo DUOX2 expression in neutrophil subsets shapes the pathogenesis of intestinal disease

By sjmartinez • May 7, 2025

Singh AK, Ainciburu M, Wynne K, Bhat SA, Blanco A, Tzani I, Akiba Y, Lalor SJ, Kaunitz J, Bourke B, Kelly VP, Doherty GA, Zerbe CS, Clarke C, Hussey S, Knaus UG. De novo DUOX2 expression in neutrophil subsets shapes the pathogenesis of intestinal disease. Proc Natl Acad Sci U S A. 2025 May 13;122(19):e2421747122. doi: 10.1073/pnas.2421747122. Epub 2025 May 6. PMID: 40327691.

Tags: Chronic Granulomatous Disease, Digestive Diseases, DUOX2 NADPH oxidase, infection, inflammatory bowel disease, Neutrophils, Publications

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