Wip1 phosphatase activator QGC-8-52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells

By sjmartinez • January 10, 2025

Wu K, Ge XX, Duan XF, Li JQ, Wang K, Chen QH, Huang ZM, Zhang WY, Wu Y, Li Q. Wip1 phosphatase activator QGC-8-52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells. Drug Resist Updat. 2024 Dec 24;79:101196. doi: 10.1016/j.drup.2024.101196. Epub ahead of print. PMID: 39787991.

Tags: breast cancer, Dephosphorylation, FOXO3a, General Internal Medicine, King Drew Med Ctr, Post Doc, Publications, TRAIL, Wip1

Indigenous Data Sovereignty in Genomics and Human Genetics: Genomic Equity and Justice for Indigenous Peoples

Halmai NB, Taitingfong R, Jennings LL, Yracheta J, Garba I, Lund JR, Curley CA, Claw KG, Taualii M, Garrison NA, Carroll SR. Indigenous Data Sovereignty[...]

Mammographic classification of interval breast cancers and artificial intelligence performance

Yu TT, Hoyt AC, Joines MM, Fischer CP, Yaghmai N, Chalfant JS, Chow L, Mortazavi S, Sears CD, Sayre J, Elmore JG, Hsu W, Milch[...]

Bone Marrow Failure in Prostate Cancer: A Rare Case Initially Disguised as Thrombotic Thrombocytopenic Purpura

Dommaraju SR, Shodiya M, Henick K. Bone Marrow Failure in Prostate Cancer: A Rare Case Initially Disguised as Thrombotic Thrombocytopenic Purpura. Cureus. 2025 Mar 18;17(3):e80781.[...]