Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation

By sjmartinez • October 27, 2024

Zhang T, Chen J, Yang H, Sun X, Ou Y, Wang Q, Edderkaoui M, Zheng S, Ren F, Tong Y, Hu R, Liu J, Gao Y, Pandol SJ, Han YP, Zheng X. Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation. Cell Mol Life Sci. 2024 Oct 26;81(1):442. doi: 10.1007/s00018-024-05466-y. PMID: 39460766; PMCID: PMC11512982.

Tags: Autophagy, Cedars Sinai DoM, Digestive Diseases, Olive View DoM, pancreatic ductal adenocarcinoma, Publications, Soft matrix, Tumor dormancy, Yes-associated protein 1

Blood Pressure Genetic Risk and Incident Hypertension at 2 to 7 Years Post Partum

Hemeryck J, De Moor N, Ezzat D, Khan RR, Vandergrift N, Levine LD, Rouse C, Theilen LH, Bairey Merz CN, Yee LM, Chung J, Bello[...]

Consensus Recommendations for Disease- and Treatment-Related Fatigue in Patients With Advanced Prostate Cancer: A Modified Delphi Panel

Freedland SJ, Aronson W, Asher A, Golant M, Lemke E, Morgans AK, Morris D, Sullivan C, Sutton J, Thomson CA, Twardowski P, Wefel JS, Winters-Stone[...]

A Multicomponent Approach to Screening for Dementia in Older Hospitalized Patients

Tan ZS, Qureshi N, Sicotte NL, Hirsch D, Escovedo C, Spivack E, Nasmyth MC, Gonzales M, Kremen SA, Nuckols TK, Mafi J, McFadden J, Roberts[...]