FAAH inhibitor URB597 shows anti-hyperalgesic action and increases brain and intestinal tissues fatty acid amides in a model of CRF1 agonist mediated visceral hypersensitivity in male rats

By sjmartinez • October 1, 2024

Larauche M, Mulak A, Ha C, Million M, Arnett S, Germano P, Pearson JP, Currie MG, Taché Y. FAAH inhibitor URB597 shows anti-hyperalgesic action and increases brain and intestinal tissues fatty acid amides in a model of CRF₁ agonist mediated visceral hypersensitivity in male rats. Neurogastroenterol Motil. 2024 Sep 30:e14927. doi: 10.1111/nmo.14927. Epub ahead of print. PMID: 39344695.

Tags: anandamide, cortagine, defecation, Digestive Diseases, Irritable Bowel Syndrome, Publications, rat, URB597, Veterans Administration, Visceral pain

Collagenous Gastritis Presenting as Chronic Nausea and Vomiting

Shahrvini B, Greb AC, Wang HL, Tripathi PV, Weiss GA, Myint A. Collagenous Gastritis Presenting as Chronic Nausea and Vomiting. ACG Case Rep J. 2026[...]

Social and clinical determinants of liver transplant evaluation in hepatocellular carcinoma: A multicenter cohort study

Tincopa M, Bridi L, Vodkin I, Yilma M, Zhou K, Kwong A, Singh J, Mehta N, Kuo A, Hirose R, Wisel SA, Steggerda JA, Freise[...]

Irritable bowel syndrome and related disorders of gut-brain interaction

Black CJ, Chuah KH, Nasser Y, Remes-Troche JM, Shin A, Ford AC. Irritable bowel syndrome and related disorders of gut-brain interaction. Lancet. 2026 Oct 29:S0140-6736(26)01500-X.[...]