Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

By sjmartinez • September 3, 2024

An J, Kurilov R, Peccerella T, Bergmann F, Edderkaoui M, Lim A, Zhou X, Pfütze K, Schulz A, Wolf S, Hu K, Springfeld C, Mughal SS, Zezlina L, Fortunato F, Beyer G, Mayerle J, Roth S, Hulkkonen J, Merz D, Ei S, Mehrabi A, Loos M, Al-Saeedi M, Michalski CW, Büchler MW, Hackert T, Brors B, Pandol SJ, Bailey P, Neoptolemos JP. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response. Transl Oncol. 2024 Aug 31;49:102109. doi: 10.1016/j.tranon.2024.102109. Epub ahead of print. PMID: 39217851.

Tags: apoptosis, Autophagy, Cedars Sinai DoM, Digestive Diseases, GSK3-β, Histone deacetylases, Molecular subtypes, pancreatic cancer, Publications

Related Posts

One-year outcomes of the RESILIA balloon-expandable transcatheter valve: survival, hemodynamics, and hypoattenuated leaflet thickening

Suruga K, Patel V, Guo Y, Shitan H, Ng D, Nagasaka T, Menda J, Singh A, Gheorghiu M, Patel D, Gupta A, Chakravarty T, Cheng[...]

Optimization of Image Quality for Quantitative Multi-Contrast Atherosclerosis Characterization (qMATCH): Comparison Between Transverse and Coronal Acquisitions

Hsu YC, Lu M, Llanes A, Keushkerian MJ, Nguyen KL, Johnson K, Altbach MI, Morris HD, DeMarco JK, Deshpande V, Mitsouras D, Saloner D, McNally[...]

Multicenter Study on the Safety of Pulsed Field Ablation in Over 40,000 Patients: MANIFEST-US

Turagam MK, Aryana A, Day JD, Dukkipati SR, Hounshell T, Nair D, Natale A, Weiner S, Cheung JW, Chinitz L, Cuoco F, Daccarett M, Dandamudi[...]