Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

By sjmartinez • September 3, 2024

An J, Kurilov R, Peccerella T, Bergmann F, Edderkaoui M, Lim A, Zhou X, Pfütze K, Schulz A, Wolf S, Hu K, Springfeld C, Mughal SS, Zezlina L, Fortunato F, Beyer G, Mayerle J, Roth S, Hulkkonen J, Merz D, Ei S, Mehrabi A, Loos M, Al-Saeedi M, Michalski CW, Büchler MW, Hackert T, Brors B, Pandol SJ, Bailey P, Neoptolemos JP. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response. Transl Oncol. 2024 Aug 31;49:102109. doi: 10.1016/j.tranon.2024.102109. Epub ahead of print. PMID: 39217851.

Tags: apoptosis, Autophagy, Cedars Sinai DoM, Digestive Diseases, GSK3-β, Histone deacetylases, Molecular subtypes, pancreatic cancer, Publications

Loss of ATP-Dependent Citrate Lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling

Liu S, Gammon ST, Tan L, Gao Y, Kim K, Elbatreek MH, Arrieta A, Williamson IK, Salazar RL, Pham J, Davidian A, Khanna Neicheril R,[...]

Exploring Features of the Parasport Environment Associated With Quality Participation

Gee CM, Evans MB, Sinden AR, Shirazipour CH, Martin Ginis KA, Latimer-Cheung AE. Exploring Features of the Parasport Environment Associated With Quality Participation. Adapt Phys[...]

Comparison of Outcomes of Leadless Versus Transvenous Pacemakers Following Tricuspid Valve Surgery

Shimoda TM, Miyamoto Y, Ueyama HA, Itagaki S, Kaneko T, Gotanda H, Inoue K, Fukuhara S, Ailawadi G, Takayama H, Kuno T, Tsugawa Y. Comparison[...]