Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

By sjmartinez • September 3, 2024

An J, Kurilov R, Peccerella T, Bergmann F, Edderkaoui M, Lim A, Zhou X, Pfütze K, Schulz A, Wolf S, Hu K, Springfeld C, Mughal SS, Zezlina L, Fortunato F, Beyer G, Mayerle J, Roth S, Hulkkonen J, Merz D, Ei S, Mehrabi A, Loos M, Al-Saeedi M, Michalski CW, Büchler MW, Hackert T, Brors B, Pandol SJ, Bailey P, Neoptolemos JP. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response. Transl Oncol. 2024 Aug 31;49:102109. doi: 10.1016/j.tranon.2024.102109. Epub ahead of print. PMID: 39217851.

Tags: apoptosis, Autophagy, Cedars Sinai DoM, Digestive Diseases, GSK3-β, Histone deacetylases, Molecular subtypes, pancreatic cancer, Publications

Elevated ctDNA Tumor Fraction Is Associated with Improved Mutation Detection but Worse Overall Survival in Advanced Non-Small Cell Lung Cancer: a Lung-MAP Study

Mack PC, Redman MW, Tukachinsky H, Kozono DE, Minichiello K, Dragnev KH, Tolba KA, Neal JW, Madison RW, Waqar SN, Aggarwal C, Hirsch FR, Patel[...]

Topic Mapping to Inform Content to Discuss in Shared Decision-Making for Prostate Cancer

Friedrich NA, Kokorowski P, Luu M, Chaplin A, Polineni R, Shiang A, Shin D, Tan J, Freedland SJ, Spiegel B, Daskivich TJ. Topic Mapping to[...]

Long-Term Outcomes Following Catheter-Based Therapies in Older Adults With Acute Pulmonary Embolism

Watanabe A, Kuno T, Miyamoto Y, Ueyama HA, Gotanda H, Bangalore S, Tsugawa Y. Long-Term Outcomes Following Catheter-Based Therapies in Older Adults With Acute Pulmonary[...]