Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness

By sjmartinez • August 22, 2024

Hatziapostolou M, Koutsioumpa M, Zaitoun AM, Polytarchou C, Edderkaoui M, Mahurkar-Joshi S, Vadakekolathu J, D'Andrea D, Lay AR, Christodoulou N, Pham T, Yau TO, Vorvis C, Chatterji S, Pandol SJ, Poultsides GA, Dawson DW, Lobo DN, Iliopoulos D. Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness. Gastro Hep Adv. 2024 Apr 24;3(5):687-702. doi: 10.1016/j.gastha.2024.04.005. PMID: 39165427; PMCID: PMC11330932.

Tags: Cedars Sinai DoM, Digestive Diseases, DNA methylation, epigenetics, HNF4A, pancreatic cancer, Publications

Improved Assessment of Coronary Artery Disease in Obese Subjects with Flurpiridaz-18F PET Myocardial Perfusion Imaging: A Prespecified Subgroup Analysis of the AURORA Phase 3 Study

Patel KK, Maddahi J, Agostini D, Bax JJ, Beanlands RSB, Berman D, Dorbala S, Heller GV, Knuuti JM, Pelletier-Galarneau M, Tamaki N, Thompson D, Somer[...]

30-Day Outcomes of a Single-Stage Transfemoral Mitral Valve Replacement System in Severe Mitral Valve Disease

Yadav PK, Vahl TP, Thourani VH, Latib A, Chehab BM, Rinaldi M, Makkar R, Rogers JH, Rodés-Cabau J, Singh G, Gössl M, Sorajja P, Reardon[...]

Single-cell and spatial omics in liver identify cell-cell communication regulators in aging and insulin resistance

Zhao W, Jiao X, Du K, Sun Q, Duan J, Cao Y, Shen X, Said Z, Karri SS, Ellsworth P, Hu W, Sargsyan A, Astapova[...]