Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

By sjmartinez • January 9, 2024

Hughes O, Bentley AR, Breeze CE, Aguet F, Xu X, Nadkarni G, Sun Q, Lin BM, Gilliland T, Meyer MC, Du J, Raffield LM, Kramer H, Morton RW, Gouveia MH, Atkinson EG, Valladares-Salgado A, Wacher-Rodarte N, Dueker ND, Guo X, Hai Y, Adeyemo A, Best LG, Cai J, Chen G, Chong M, Doumatey A, Eales J, Goodarzi MO, Ipp E, Irvin MR, Jiang M, Jones AC, Kooperberg C, Krieger JE, Lange EM, Lanktree MB, Lash JP, Lotufo PA, Loos RJF, Ha My VT, Peralta-Romero J, Qi L, Raffel LJ, Rich SS, Rodriquez EJ, Tarazona-Santos E, Taylor KD, Umans JG, Wen J, Young BA, Yu Z, Zhang Y, Ida Chen YD, Rundek T, Rotter JI, Cruz M, Fornage M, Lima-Costa MF, Pereira AC, Paré G, Natarajan P, Cole SA, Carson AP, Lange LA, Li Y, Perez-Stable EJ, Do R, Charchar FJ, Tomaszewski M, Mychaleckyj JC, Rotimi C, Morris AP, Franceschini N. Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. Cell Genom. 2023 Dec 20:100468. doi: 10.1016/j.xgen.2023.100468. Epub ahead of print. PMID: 38190104.

Tags: admixed populations, Cedars Sinai DoM, Chronic kidney disease, EGFR, Endocrinology, expression quantitative trait locus, fine-mapping, Genome-wide association study, kidney function, multi-ancestry, polygenic scores, Publications

Comparison, Agreement, and Significance Cutoffs of 18F-Flurpiridaz PET Myocardial Blood Flow Quantitation Methods and Software Packages

Packard RRS, Buckley C, Cooke CD, Moody JB, Renaud JM, Slomka P, Thompson D, Van Kriekinge SD, Van Train KF, Wangerin KA, Maddahi J. Comparison,[...]

The REgistry of Flow and Perfusion Imaging for Artificial INtelligEnce with PET(REFINE PET): Rationale and Design

Ramirez G, Lemley M, Shanbhag A, Kwiecinski J, Miller RJH, Kavanagh PB, Liang JX, Dey D, Slipczuk L, Travin MI, Alexanderson E, Carvajal-Juarez I, Packard[...]

Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice

Sendo S, Vela AJ, Ro M, Thiruppathy D, Wilkinson EL, Zhao Z, Hsieh WC, Yang S, Coras R, Bergot AS, Guma M, Nguyen A, McBride[...]