Lipophilic statins inhibit YAP co-activator transcriptional activity in HCC cells through Rho-mediated modulation of the actin cytoskeleton

By sjmartinez • June 28, 2023

Benhammou JN, Qiao B, Ko A, Sinnett-Smith J, Pisegna J, Rozengurt E. Lipophilic statins inhibit YAP co-activator transcriptional activity in HCC cells through Rho-mediated modulation of the actin cytoskeleton. Am J Physiol Gastrointest Liver Physiol. 2023 Jun 27. doi: 10.1152/ajpgi.00089.2023. Epub ahead of print. PMID: 37366601.

Tags: chemoprevention, Digestive Diseases, Hepatocellular carcinoma, Publications, Statins, Veterans Administration, YAP

Patient Preferences in Hepatocellular Carcinoma Surveillance: A Multi-site Conjoint Analysis

Kao KD, Troost JP, Yang JD, Salgia R, Woolen SA, Mehta N, Hoteit MA, Jalal PK, El Dahan KS, Daher D, Quirk L, Patel N,[...]

Transoral outlet reduction zipper technique for enhanced tissue approximation and potential improved durability

Quon CM, Garcia-Corella J, Bahdi F, Issa D. Transoral outlet reduction zipper technique for enhanced tissue approximation and potential improved durability. VideoGIE. 2025 Oct 11;11(4):140-143.[...]

Malignancy in Long-Standing Perianal Fistulizing Crohn’s Disease: Too Little, Too Late

Goyal A, Syal G, Fleshner P, Gu P. Malignancy in Long-Standing Perianal Fistulizing Crohn's Disease: Too Little, Too Late. Dig Dis Sci. 2026 Apr 13.[...]