Macrophage fumarate hydratase restrains mtRNA-mediated interferon production

By sjmartinez • March 9, 2023

Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ. Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature. 2023 Mar 8. doi: 10.1038/s41586-023-05720-6. Epub ahead of print. PMID: 36890227.

Tags: Cedars Sinai DoM, Publications, Rheumatology

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