Combinations of Daptomycin plus Ceftriaxone, but Not Ascending Daptomycin Dose-Regimens, Are Effective in Experimental Endocarditis Caused by Streptococcus mitis -oralis Strains: Target Tissue Clearances and Prevention of Emergence of Daptomycin-Resistance

Mishra NN, Abdelhady W, Elsayed AM, Lapitan C, Proctor RA, Rybak MJ, Miro JM, Bayer AS. Combinations of Daptomycin plus Ceftriaxone, but Not Ascending Daptomycin Dose-Regimens, Are Effective in Experimental Endocarditis Caused by Streptococcus mitis-oralis Strains: Target Tissue Clearances and Prevention of Emergence of Daptomycin-Resistance. Antimicrob Agents Chemother. 2023 Mar 6:e0147222. doi: 10.1128/aac.01472-22. Epub ahead of print. PMID: 36877026.


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