The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR

By sjmartinez • August 5, 2022

Steffen J, Ngo J, Wang SP, Williams K, Kramer HF, Ho G, Rodriguez C, Yekkala K, Amuzie C, Bialecki R, Norquay L, Nawrocki AR, Erion M, Pocai A, Shirihai OS, Liesa M. The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR. Mol Metab. 2022 Aug 5:101566. doi: 10.1016/j.molmet.2022.101566. Epub ahead of print. PMID: 35940556.

Tags: ATF4, Drp1, Endocrinology, ISR, mitochondria, NASH, Oma1, Publications

Menopausal Transition and Thyroid Function Trajectories: A Large-Scale Longitudinal Study of Healthy Women

Hayashi S, Fukui S, Leung AM, Noto H, Inoue K. Menopausal Transition and Thyroid Function Trajectories: A Large-Scale Longitudinal Study of Healthy Women. J Clin[...]

E. Dale Abel, MD, PhD Awarded Jamaica’s Order of Distinction, Commander Class

The UCLA Department of Medicine is proud to announce that E. Dale Abel, MD, PhD, chair and executive medical director of the Department of Medicine[...]

Incidence, Risk Factors, and Survival Implications of Immune-Related Adverse Events in Patients With Metastatic Breast Cancer

Baclig NV, Chengappa M, Soliman AJ, Jacob S, LeVee A, Fisch S, Face C, Chaudhry S, Idossa D, Poonacha T, Huppert L, Quintal L, Melisko[...]