Distinct connectivity patterns subserve 2 dimensions of the chronic pain experience

By afschroeder • September 29, 2026

McLain NJ, Kaplan CM, Naliboff BD, Rodriguez L, Moldwin R, Williams DA, Farrar JT, Harris RE, Spitznagle T, Clauw D, Clemens JQ, Harte SE, Kutch JJ, Schrepf A. Distinct connectivity patterns subserve 2 dimensions of the chronic pain experience. Pain. 2026 Sep 24. doi: 10.1097/j.pain.0000000000004114. Epub ahead of print. PMID: 42806761.

Tags: chronic pain, Chronic pelvic pain, Clinical pain, Digestive Diseases, Evoked pain, FMRI, functional connectivity, Publications, UCPPS

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JPEN Journal Club 104. Pragmatic trials

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