Dietary α-ketoglutarate modulates lung adenocarcinoma growth and epigenetic remodeling in a sex-dependent fashion

By afschroeder • September 24, 2026

Alcaraz M Jr, Pandey A, Santiago M, Dumitras C, Pradis L, Gomez E, Soto A, Saggese P, Krall AS, Liu B, Christofk HR, Dubinett SM, Li X, Scafoglio C. Dietary α-ketoglutarate modulates lung adenocarcinoma growth and epigenetic remodeling in a sex-dependent fashion. Cell Rep. 2026 Sep 23;45(10):118052. doi: 10.1016/j.celrep.2026.118052. Epub ahead of print. PMID: 42776841.

Tags: chemoprevention, CP: cancer, dietary supplement, differentiation, epigenetics, histone methylation, Lung cancer, Metabolism, Post Doc, Publications, Pulmonary, Critical Care & Sleep Medicine, Sexual dimorphism, Tbx5, α-ketoglutarate

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