Coenzyme A activates TLR4 and enhances alternative macrophage activation in line with MyD88 agonism

By afschroeder • September 19, 2026

Jones AE, Rios A, Ibrahimovic N, Ball AB, Chavez C, Bayley NA, Falta NA, Mekkittikul M, Carrillo C, Hsieh WY, Sammarco A, Reyes AB, Cortez AA, Graeber TG, Watson RL, Hoffmann A, Bensinger SJ, Divakaruni AS. Coenzyme A activates TLR4 and enhances alternative macrophage activation in line with MyD88 agonism. EMBO Rep. 2026 Sep 18. doi: 10.1038/s44319-026-00925-y. Epub ahead of print. PMID: 42760443.

Tags: Publications, Pulmonary, Critical Care & Sleep Medicine

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