Hepatic stellate cell subpopulations in human MASLD-related hepatocellular carcinoma upregulate YAP via geranylgeranyl pyrophosphate

By afschroeder • August 19, 2026

Labrecque CL, Ko A, Qiao B, Pan C, Nandakumar R, Chowdhury K, Venkatesan N, Du X, Cai B, Pellegrini M, Pisegna JR, French SW, Agopian V, Rozengurt E, Singh R, Benhammou JN. Hepatic stellate cell subpopulations in human MASLD-related hepatocellular carcinoma upregulate YAP via geranylgeranyl pyrophosphate. Hepatol Commun. 2026 Aug 14;10(9):e1015. doi: 10.1097/HC9.0000000000001015. PMID: 42612117; PMCID: PMC13480919.

Tags: Digestive Diseases, geranylgeranyl pyrophosphate, Hepatocellular carcinoma, Post Doc, Publications, Rho GTPases, single-nucleus RNA sequencing, spatial imaging, Statins, Veterans Administration, yes-associated protein

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