Metabolic atlas of early human cortex reveals glycolytic remodeling and pentose phosphate pathway control of cell fate transitions

By afschroeder • August 5, 2026

Mil J, Soto JA, Krall AS, Peloggia J, Frigui S, Fong OS, Sathe L, Matulionis N, Day F, Stiles L, Montales KP, Azizad DJ, Gonzalez CE, Fazzari E, Li MX, Nano PR, Martija AA, Perez-Ramirez CA, Nguyen CV, Wick B, Ge W, Kan RL, Andrews MG, Haeussler M, Wells MF, Christofk HR, Bhaduri A. Metabolic atlas of early human cortex reveals glycolytic remodeling and pentose phosphate pathway control of cell fate transitions. Cell. 2026 Aug 4:S0092-8674(26)00821-4. doi: 10.1016/j.cell.2026.07.023. Epub ahead of print. PMID: 42551423.

Tags: cell fate, cortical development, cortical organoids, Endocrinology, glycolysis, Metabolism, metabolomics, neurodevelopment, pentose phosphate pathway, Publications, radial glia

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