TroFuse-011 study design: sacituzumab tirumotecan with or without pembrolizumab for advanced triple-negative breast cancer with PD-L1 CPS <10

By afschroeder • August 1, 2026

Rugo HS, Schmid P, Cortes J, Takano T, Fasching PA, Park YH, Bianchini G, Franco SX, Villarreal-Garza C, Tredan O, Yin Y, Barroso-Sousa R, Peng X, Malhotra U, Smith KL, Bardia A. TroFuse-011 study design: sacituzumab tirumotecan with or without pembrolizumab for advanced triple-negative breast cancer with PD-L1 CPS <10. Future Oncol. 2026 Aug;22(18):2121-2129. doi: 10.1080/14796694.2026.2701483. Epub 2026 Jul 31. PMID: 42535874.

Tags: antibody-drug conjugate, Clinical trial protocol, Hematology/Oncology, PD-L1 CPS <10, pembrolizumab, Phase III, Publications, sacituzumab tirumotecan, targeted therapy, triple-negative breast cancer

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