Gut bacterial metabolite imidazole propionate potentiates Alzheimer’s disease pathology

Vemuganti V, Kang JW, Zhang Q, McGregor ER, Hilser JR, Aquino-Martinez R, Harding S, Harpt JL, Beck KR, Bussan H, Kuehn JF, Deming Y, Studer R, Johnson SC, Asthana S, Zetterberg H, Blennow K, Engelman CD, Allayee H, Anderson RM, Ulland TK, Bäckhed F, Bendlin BB, Rey FE. Gut bacterial metabolite imidazole propionate potentiates Alzheimer's disease pathology. Nat Commun. 2026 Jun 26. doi: 10.1038/s41467-026-74744-z. Epub ahead of print. PMID: 42362546.


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