Patterns of Adherence and Persistence to Triple and Quadruple Guideline-Directed Medical Therapy Among US Patients With Heart Failure With Reduced Ejection Fraction

By afschroeder • April 29, 2026

Fonarow GC, Coyle CR, Obi EN, Marks-Anglin AK, Alipour-Haris G, Stevenson AS. Patterns of Adherence and Persistence to Triple and Quadruple Guideline-Directed Medical Therapy Among US Patients With Heart Failure With Reduced Ejection Fraction. J Am Heart Assoc. 2026 Apr 28:e046643. doi: 10.1161/JAHA.125.046643. Epub ahead of print. PMID: 42047207.

Tags: Cardiology/Epi, combination drug therapy, guideline‐directed medical therapy, Heart failure with reduced ejection fraction, medication adherence, persistence, Publications

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