Toward the simultaneous detection of multiple diseases with a highly cost-effective cell-free DNA methylome test

By afschroeder • April 7, 2026

Zeng W, Liu CC, Li S, Zhou Y, Stackpole ML, Xiao Y, Hu R, Tang C, Liu Q, Zeng W, Yeh A, Melehy A, Tran B, Noor Z, Yokomizo M, Amara D, Gumate S, Ahuja P, Li DY, Zhao J, Rose I, Walker C, Malik S, Zhu Y, Tseng HR, Garon EB, French SW, Magyar CE, Dry SM, Lajonchere CM, Geschwind D, Choi G, Saab S, Shetty A, Wong CR, King KG, Lu DS, Raman SS, Xiang X, Shetty K, Mishra L, Memarzadeh S, Liu Y, Albe F, Hsu W, Krysan K, Dubinett SM, Aberle DR, Agopian V, Han SB, Wong WH, Ni X, Li W, Zhou XJ. Toward the simultaneous detection of multiple diseases with a highly cost-effective cell-free DNA methylome test. Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2518347123. doi: 10.1073/pnas.2518347123. Epub 2026 Apr 6. PMID: 41941615.

Tags: Cancer detection, cell-free DNA, Digestive Diseases, disease detection, DNA methylation, General Internal Medicine, Hematology/Oncology, Hospitalist, Liquid biopsy, Publications, Pulmonary, Critical Care & Sleep Medicine

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