Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial

By afschroeder • March 27, 2026

Das JK, Zhang Y, Redman LM, Martin CK, Das SK, Racette SB, Herbst A, Liu N, Allison DB, McKenzie D, Aiken JM, Horvath S, Candia J, Banskota N, Ferrucci L, Kraus WE, Huffman KM, Wanagat J. Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial. Geroscience. 2026 Mar 26. doi: 10.1007/s11357-026-02167-1. Epub ahead of print. PMID: 41886216.

Tags: calorie restriction, DNA, gene expression, Geriatrics, human, mitochondria, mutation, Publications, Veterans Administration

Drp1 regulates mitochondrial health and controls skeletal muscle mass through the Erk1/2-Nur77 pathway

Ma AM, Tran PH, Yang NL, Ngo J, Iwasaki H, Ren W, Livit S, Stiles L, Wang S, Ho T, Yim EY, Morrow N, Johnson[...]

Associations between sedentary behavior and allostatic load: The 1970 British Cohort Study

Chauntry AJ, Diana JC, Li Q, Seeman T, Courtney JB, Tyne WP, Whittaker AC, Turner AI, Teychenne M, Lassalle PP, Zieff G, Gibbs BB, Diaz[...]

Progressive Muscle Rigidity and Spasms in an Older Adult: A Diagnostic Challenge

Leonard SD, Tran HT. Progressive Muscle Rigidity and Spasms in an Older Adult: A Diagnostic Challenge. Cureus. 2026 Apr 2;18(4):e106329. doi: 10.7759/cureus.106329. PMID: 42078214; PMCID:[...]