Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 4)

Qaseem A, Owens DK, Etxeandia-Ikobaltzeta I, Cross JT Jr, Yost J, Crandall CJ; Clinical Guidelines Committee of the American College of Physicians; Balk EM, Fitterman N, Gibson M, Lewis J, Mackey K, Miller MC, Obley AJ, Shekelle PG, Tice JA, Carroll K, Harrod CS, Shamliyan T, Vigna C; Clinical Guidelines Committee of the American College of Physicians*. Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians (Version 1, Update Alert 4). Ann Intern Med. 2026 Mar 10. doi: 10.7326/ANNALS-26-00548. Epub ahead of print. PMID: 41802255.


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