A CD57+ CD8 T cell subset links cytotoxic T cell cytotoxicity to fibrotic lung disease in systemic sclerosis

By afschroeder • February 18, 2026

Sasaki T, Cao Y, Sowerby JM, Higashioka K, Marks KE, Elahee M, Kamiya M, Dellaripa PF, Ainsworth RI, Taylor KE, Bottini N, Wolters P, Kim EY, Boin F, Rao DA. A CD57+ CD8 T cell subset links cytotoxic T cell cytotoxicity to fibrotic lung disease in systemic sclerosis. J Clin Invest. 2026 Feb 17:e194288. doi: 10.1172/JCI194288. Epub ahead of print. PMID: 41701649.

Tags: autoimmunity, Cedars Sinai DoM, Immunology, Publications, Rheumatology, T cells

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