NALIRIFOX versus nab-paclitaxel and gemcitabine in older patients with treatment-naive metastatic pancreatic cancer: a subgroup analysis of the pivotal NAPOLI 3 trial

By afschroeder • February 14, 2026

Macarulla T, Cid RP, Womack MS, Gracian AC, Zervoudakis A, Hatoum H, Chung V, Patel A, Paulson AS, Pant S, O'Reilly EM, Hubner RA, Van Cutsem E, Bekaii-Saab T, Zhang L, Li J, Chen H, Maxwell F, Wainberg ZA, Melisi D. NALIRIFOX versus nab-paclitaxel and gemcitabine in older patients with treatment-naive metastatic pancreatic cancer: a subgroup analysis of the pivotal NAPOLI 3 trial. ESMO Open. 2026 Feb 12;11(3):106043. doi: 10.1016/j.esmoop.2025.106043. Epub ahead of print. PMID: 41687160.

Tags: age, Hematology/Oncology, Liposomal irinotecan, mPDAC, NALIRIFOX, NAPOLI 3, pancreatic ductal adenocarcinoma, Publications

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