Halofuginone Suppresses Hepcidin by a Heparan Sulfate-dependent Mechanism to Treat Iron Disorders in Mice

By afschroeder • February 12, 2026

Leal S, Denardo A, Van Echten A, Jungnickel H, Nelson CB, Sandoval D, Salvador JA, Shin J, Chung A, Brush M, Bennett CP, Piermatteo A, Secrest P, Jung CL, Ganz T, Poli M, Gordts P. Halofuginone Suppresses Hepcidin by a Heparan Sulfate-dependent Mechanism to Treat Iron Disorders in Mice. Blood Adv. 2026 Feb 11:bloodadvances.2025017943. doi: 10.1182/bloodadvances.2025017943. Epub ahead of print. PMID: 41671472.

Tags: Publications, Pulmonary, Critical Care & Sleep Medicine

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