Gain of function NOTCH4 variants disrupt angiogenesis in systemic sclerosis

By afschroeder • February 6, 2026

Kaundal U, Tsou PS, Sahu M, Huang M, Boyden SE, Woodford CM, Shriner D, Stenson E, Safran SA, Zhou Y, Talley TA, Gudapati K, Zhang X, Kunishita Y, Wang J, Shah AA, Mayes MD, Doumatey AP, Bentley AR, Domsic R, Medsger TA Jr, Ramos PS, Silver RM, Steen V, Varga J, Hsu V, Saketkoo LA, Schiopu E, Gordon JK, Criswell LA, Gladue H, Derk C, Bernstein EJ, Bridges SL Jr, Shanmugam V, Chung L, Kafaja S, Jan R, Trojanowski M, Goldberg A, Korman BD, Mullikin J, Thomas JW, Dell'Orso S, Randazzo D, Adeyemo A, Remmers EF, Schwartzberg PL, Aksentijevich I, Rotimi C, Wigley FM, Wang RA, Boin F, Khanna D, Lafyatis R, Kastner DL, Gourh P. Gain of function NOTCH4 variants disrupt angiogenesis in systemic sclerosis. Ann Rheum Dis. 2026 Feb 4:S0003-4967(25)04609-6. doi: 10.1016/j.ard.2025.12.015. Epub ahead of print. PMID: 41644364.

Tags: Cedars Sinai DoM, Publications, Rheumatology

Optimization of Image Quality for Quantitative Multicontrast Atherosclerosis Characterization (qMATCH): Comparison between Transverse and Coronal Acquisitions

Hsu YC, Lu M, Llanes A, Keushkerian MJ, Nguyen KL, Johnson K, Altbach MI, Morris HD, DeMarco JK, Deshpande V, Mitsouras D, Saloner D, McNally[...]

Investments in Childhood Community Resources and Subsequent Adult Health Outcomes

La Charite J, Dudovitz R, Choi K, Chen K, Jackson NJ, Nuckols T, Sastry N, Schickedanz A, Wong MD, Zimmerman FJ. Investments in Childhood Community[...]

Short-term outcomes of laparoscopic hiatal hernia repair with consecutive transoral incisionless fundoplication (cTIF): a prospective multicenter cohort study

Kolb JM, Canto MI, Parker B, Murray M, Brewer Gutierrez OI, Sharaiha RZ, Samarasena J, Thosani NC, Abu-Dayyeh BK, Janu P, Chang KJ, Nguyen NT.[...]