Loss of ROR2 Tyrosine Kinase Receptor Is Associated With Endothelial Dysfunction in PAH via Inappropriate Integrin Beta1 Activation

By afschroeder • February 5, 2026

Mitra A, Agarwal S, Chakraborty A, Zhong BL, Heo L, Roy A, Bankar A, Pacheco A, Auer N, Dunn A, Chelladurai P, Jain A, Matos Muñoz JA, Guardado ES, Yi D, Zhao H, Man KWD, Nair R, Hong J, Kuebler WM, Guenat OT, Dai Z, de Jesus Perez VA. Loss of ROR2 Tyrosine Kinase Receptor Is Associated With Endothelial Dysfunction in PAH via Inappropriate Integrin β1 Activation. Hypertension. 2026 Feb 4. doi: 10.1161/HYPERTENSIONAHA.125.25881. Epub ahead of print. PMID: 41636059.

Tags: cell polarity, Endothelial cells, focal adhesion, Publications, pulmonary arterial hypertension, Pulmonary, Critical Care & Sleep Medicine, Vascular remodeling

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