ERalpha activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness

By afschroeder • January 8, 2026

Hu R, Park J, Qian Y, Xiong S, Elsabbagh AH, Chhikara A, Fan H, Shi Z, Liu L, Li Y, Song Z, Mahmoud AM, Chen J, Baur JA, He Y, Layden BT, Zhou Z, Xu P, Ong SG, Wang Z, Jiang Y. ERα activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness. Sci Adv. 2026 Jan 9;12(2):eadz1385. doi: 10.1126/sciadv.adz1385. Epub 2026 Jan 7. PMID: 41499496.

Tags: Endocrinology, Publications

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