Testosterone deficiency synergistically exacerbates fructose-induced hepatic steatosis through gut microbiota and pyruvate in mice

By afschroeder • January 7, 2026

Takahashi H, Harada N, Hayamizu Y, Dungubat E, Nakazawa M, Kitakaze T, Sugimoto K, Inui H, Yoshihara E, Takahashi Y, Yamaji R. Testosterone deficiency synergistically exacerbates fructose-induced hepatic steatosis through gut microbiota and pyruvate in mice. Am J Physiol Endocrinol Metab. 2026 Jan 6. doi: 10.1152/ajpendo.00518.2025. Epub ahead of print. PMID: 41494643.

Tags: Androgen, castration, Endocrinology, Fatty Liver, Gut microbiome, Harbor UCLA, Publications, pyruvate

Menopausal Transition and Thyroid Function Trajectories: A Large-Scale Longitudinal Study of Healthy Women

Hayashi S, Fukui S, Leung AM, Noto H, Inoue K. Menopausal Transition and Thyroid Function Trajectories: A Large-Scale Longitudinal Study of Healthy Women. J Clin[...]

E. Dale Abel, MD, PhD Awarded Jamaica’s Order of Distinction, Commander Class

The UCLA Department of Medicine is proud to announce that E. Dale Abel, MD, PhD, chair and executive medical director of the Department of Medicine[...]

Incidence, Risk Factors, and Survival Implications of Immune-Related Adverse Events in Patients With Metastatic Breast Cancer

Baclig NV, Chengappa M, Soliman AJ, Jacob S, LeVee A, Fisch S, Face C, Chaudhry S, Idossa D, Poonacha T, Huppert L, Quintal L, Melisko[...]