CRISPR/Cas strategies to enhance CAR T-cell function and persistence via metabolic reprogramming

By afschroeder • January 7, 2026

Wang MR, Mu W, Zhen A, Kitchen SG. CRISPR/Cas strategies to enhance CAR T-cell function and persistence via metabolic reprogramming. Trends Biotechnol. 2026 Jan 5:S0167-7799(25)00499-8. doi: 10.1016/j.tibtech.2025.12.001. Epub ahead of print. PMID: 41494892.

Tags: CAR-T, CRISPR/Cas, exhaustion, General Internal Medicine, Hematology/Oncology, Metabolism, persistence, Publications, Resident

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