SPHERES: innovative registry addressing the new era of neuromyelitis optica spectrum disorders (NMOSD) therapy

By sjmartinez • December 26, 2025

Bennett JL, Middaugh N, Yeaman MR, Smith TJ, Behne MK, Crabtree M, McLean RR, Pappas DA, Levy M. SPHERES: innovative registry addressing the new era of neuromyelitis optica spectrum disorders (NMOSD) therapy. Mult Scler Relat Disord. 2025 Dec 19;107:106940. doi: 10.1016/j.msard.2025.106940. Epub ahead of print. PMID: 41447909.

Tags: Disease activity measures, Guthy-Jackson Charitable Foundation, Harbor UCLA, Infectious Diseases, neuromyelitis optica spectrum disorders, nmosd, Patient reported outcomes, PROs, prospective observational cohort, Publications, real-world data, SPHERES registry

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