A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn’s disease

By afschroeder • December 23, 2025

Lowe SC, Leitman M, Yan N, Hoffmann A. A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn's disease. Front Immunol. 2025 Dec 4;16:1707719. doi: 10.3389/fimmu.2025.1707719. PMID: 41425579; PMCID: PMC12711780.

Tags: Crohn’s disease, Digestive Diseases, inflammatory bowel disease, Macrophage Polarization, Macrophages, mucosal immunology, Publications, ScRNAseq

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