Epigenomic study of the lower airway reveals COPD-associated methylation patterns and potential microbiota links

By afschroeder • December 20, 2025

Cao S, Shrivastav A, Bleecker ER, Madapoosi S, Erb-Downward J, Zein J, Chen X, Howard TD, Hawkins GA, Barjaktarevic IZ, Bowler R, Barr RG, Comellas A, Cooper CB, Couper D, Han M, Hansel NN, Hastie AT, Kaner R, Kanner RE, Kim V, Martinez FJ, Moore WC, O'Neal WK, Paine R, Smith B, Hoffman EA, Meyers DA, Woodruff PG, Christenson S, Curtis JL, Huang YJ, Ortega VE. Epigenomic study of the lower airway reveals COPD-associated methylation patterns and potential microbiota links. BMJ Open Respir Res. 2025 Dec 18;12(1):e003572. doi: 10.1136/bmjresp-2025-003572. PMID: 41419234; PMCID: PMC12716595.

Tags: airway epithelium, chronic obstructive, Publications, Pulmonary Disease, Pulmonary, Critical Care & Sleep Medicine

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