The mechanism of action of digoxin requires the sodium-dependent inactivation of the sodium-calcium exchanger

By afschroeder • December 18, 2025

Scranton K, John S, Angelini M, Zhang R, Schwingshackl A, Goldhaber JI, Olcese R, Ottolia M. The mechanism of action of digoxin requires the sodium-dependent inactivation of the sodium-calcium exchanger. Sci Adv. 2025 Dec 19;11(51):eady9596. doi: 10.1126/sciadv.ady9596. Epub 2025 Dec 17. PMID: 41406234.

Tags: Cardiology/Epi, Cedars Sinai DoM, Publications

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