CD2 targeted nanoparticles containing IL-2 mimic fetal-maternal tolerance of pregnancy by inducing synergistic TGF-β-producing NK cells and Tregs

By afschroeder • December 10, 2025

Horwitz DA, La Cava A. CD2 targeted nanoparticles containing IL-2 mimic fetal-maternal tolerance of pregnancy by inducing synergistic TGF-β-producing NK cells and Tregs. Front Immunol. 2025 Nov 24;16:1692547. doi: 10.3389/fimmu.2025.1692547. PMID: 41368646; PMCID: PMC12682870.

Tags: maternal-fetal tolerance, nanoparticles, natural killer (NK) cells, Publications, Rheumatology, T regulatory cells (Tregs), transforming growth factor β (TGF-β)

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