Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension

By afschroeder • December 4, 2025

Woodcock CC, Maroli G, Kim H, Tai YY, Tang Y, Okawa S, Homsi R, Kim Y, Cho ST, Jiang S, Chauvet C, Wang B, Al Aaraj Y, Lafyatis R, Saggar R, Sembrat J, Wang Q, Li Q, Frump AL, Lahm T, McCubbrey AL, Kudryashova TV, Goncharova EA, Nouraie SM, Bertero T, Yuan K, Pullamsetti SS, Chan SY. Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension. Circ Res. 2025 Dec 4. doi: 10.1161/CIRCRESAHA.125.326277. Epub ahead of print. PMID: 41342206.

Tags: apoptosis, Endothelial cells, interferon, nocturnin, Publications, pulmonary artery, Pulmonary, Critical Care & Sleep Medicine

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