The Effectiveness of Plecanatide for Treating Constipation and Bloating in Patients Aged 18 to 40 Years With Irritable Bowel Syndrome: Utilization of a New Composite Trisymptom Endpoint

By afschroeder • November 11, 2025

Brenner DM, Shin AS, Laitman AP, Deutsch JK, Kunkel DC. The Effectiveness of Plecanatide for Treating Constipation and Bloating in Patients Aged 18 to 40 Years With Irritable Bowel Syndrome: Utilization of a New Composite Trisymptom Endpoint. J Gastroenterol Hepatol. 2025 Nov 10. doi: 10.1111/jgh.70119. Epub ahead of print. PMID: 41214272.

Tags: abdominal pain, bloating, constipation, Digestive Diseases, guanylate cyclase C agonists, Irritable Bowel Syndrome, Publications

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