Altered Sigmoid Mucosal Innervation and Mast Cell Proximity to Sensory Nerve Fibers Are Associated With Symptom Severity in Patients With Irritable Bowel Syndrome

By afschroeder • November 3, 2025

Yuan PQ, Nash M, Li T, Mahurkar-Joshi S, Sohn J, Khandadash A, Taché Y, Chang L. Altered Sigmoid Mucosal Innervation and Mast Cell Proximity to Sensory Nerve Fibers Are Associated With Symptom Severity in Patients With Irritable Bowel Syndrome. Neurogastroenterol Motil. 2025 Nov 2:e70199. doi: 10.1111/nmo.70199. Epub ahead of print. PMID: 41177834.

Tags: abdominal pain, Digestive Diseases, enteric cholinergic fibers, General Internal Medicine, Irritable Bowel Syndrome, Mast cells, Publications, Resident, substance P, vasoactive intestinal peptide

Standardized Assessment of Complete Colorectal Polyp Resection for Polyps <20 mm (SCOPE): a Delphi Consensus

van Bokhorst QNE, Yarra S, van der Vlugt M, Pohl H, Dekker E, Shaukat A; SCOPE initiative collaborators. Standardized Assessment of Complete Colorectal Polyp Resection[...]

Assessing Treatment Response in Patients With IBS-C in Clinical Practice: Consensus Expert Recommendations Using a Modified Delphi Process

Sayuk GS, Filipenko D, Kornalska K, Swinburn P, Chang L. Assessing Treatment Response in Patients With IBS-C in Clinical Practice: Consensus Expert Recommendations Using a[...]

Hepatic stellate cell subpopulations in human MASLD-related hepatocellular carcinoma upregulate YAP via geranylgeranyl pyrophosphate

Labrecque CL, Ko A, Qiao B, Pan C, Nandakumar R, Chowdhury K, Venkatesan N, Du X, Cai B, Pellegrini M, Pisegna JR, French SW, Agopian[...]