Antiretroviral Therapy Intensification With Dolutegravir and/or Maraviroc Did Not Affect HIV-1 Cell-Associated DNA, RNA, and 2–LTR Circles Over 12 Weeks

By afschroeder • October 28, 2025

Reed JC, Hall L, McKhann A, Kwak G, Goecker EA, Coombs RW, Chen H, Roa J, Vecchio A, Daar ES, Hunt PW, Marra CM, Campbell TB, Ma Q, Swaminathan S, Macatangay BJC, Morse GD, Miller T, Rusin D, Ha B, Alston-Smith B, Paul R, Letendre SL, Spudich SS, Greninger AL. Antiretroviral Therapy Intensification With Dolutegravir and/or Maraviroc Did Not Affect HIV-1 Cell-Associated DNA, RNA, and 2--LTR Circles Over 12 Weeks. Open Forum Infect Dis. 2025 Oct 1;12(10):ofaf594. doi: 10.1093/ofid/ofaf594. PMID: 41141451; PMCID: PMC12548372.

Tags: 2-LTR, ART intensification, ddPCR, dolutegravir, Harbor UCLA, HIV, Infectious Diseases, Maraviroc, Publications, reservoir

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