The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice

By afschroeder • October 25, 2025

In Het Panhuis W, Thiemann E, van Dijk DMAH, Been B, Jarrett KE, Meurs A, Kooijman S, Hovingh MV, Modder M, van Os BW, Sluiter TJ, Blomberg N, Pronk ACM, Afkir S, Streefland TCM, Lalai RA, Taveras MO, Zhang S, Adams TE, Terry LV, Turpin-Nolan SM, de Vries MR, Giera M, Rose-John S, Zelcer N, de Boer JF, de Aguiar Vallim TQ, Febbraio MA, Rensen PCN, Schönke M. The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice. Sci Adv. 2025 Oct 24;11(43):eadx3794. doi: 10.1126/sciadv.adx3794. Epub 2025 Oct 24. PMID: 41134879; PMCID: PMC12551718.

Tags: Cardiology/Epi, Publications

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