Sympathovagal crosstalk: Y2-receptor blockade enhances vagal effects which in turn Reduce NPY levels via muscarinic receptor activation

By afschroeder • October 7, 2025

Jani NR, van Weperen VYH, Ayagama T, Hoang JD, Emamimeybodi M, Bussmann BM, Bal S, Kumar A, Khaky A, Hamon D, Herring N, Smith C, Vaseghi M. Sympathovagal crosstalk: Y2-receptor blockade enhances vagal effects which in turn Reduce NPY levels via muscarinic receptor activation. Cardiovasc Res. 2025 Oct 6:cvaf180. doi: 10.1093/cvr/cvaf180. Epub ahead of print. PMID: 41052902.

Tags: Cardiac Autonomic Nervous System, Cardiology/Epi, Muscarinic Receptors, neuropeptide Y, Publications, Sympathetic, vagus nerve stimulation, Y2 Receptor

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