IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation

By afschroeder • September 28, 2025

Sharma G, Gutierrez M, Jones AE, Kapoor S, Jaiswal AK, Neeb ZT, Rios A, Dorairaj P, Thaxton ML, Lin TL, Tran TM, Kabbani LES, Ritter AJ, Scherer GM, Sorrentino JP, Stiles L, Hoeve JT, Damoiseaux RD, Garg NK, Divakaruni AS, Sanford JR, Rao DS. IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation. Cell Rep. 2025 Sep 26:116330. doi: 10.1016/j.celrep.2025.116330. Epub ahead of print. PMID: 41015030.

Tags: B-acute lymphoblastic leukemia, CP: Metabolism, epitranscriptomics, Hematology/Oncology, MLL-rearranged leukemia, Publications, RNA-binding protein

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