Lysosomal LRRC8 complex impacts lysosomal pH, morphology, and systemic glucose metabolism

By afschroeder • September 27, 2025

Kumar A, Zhao Y, Xie L, Chadda R, Tranter JD, Mikami RT, Abraham N, Hong J, Feng E, Rawnsley DR, Liu H, Henry KM, Meyer G, Hu M, Xu H, Hinton A Jr, Grueter CE, Abel ED, Norris AW, Diwan A, Sah R. Lysosomal LRRC8 complex impacts lysosomal pH, morphology, and systemic glucose metabolism. Sci Adv. 2025 Sep 26;11(39):eadt6366. doi: 10.1126/sciadv.adt6366. Epub 2025 Sep 26. PMID: 41004571; PMCID: PMC12466849.

Tags: Endocrinology, Publications

Regular Insulin Versus NPH Insulin for Continuous Enteral Tube Feeding in Hospitalized Patients

Kalangi ST, Bokka SM, Anand S, Garg R. Regular Insulin Versus NPH Insulin for Continuous Enteral Tube Feeding in Hospitalized Patients. Clin Diabetes. 2025 Apr[...]

Real-World Interventions for Type 2 Diabetes Prevention (REALITY): A Multisite Study to Assess the Effectiveness and Cost-Effectiveness of the National Diabetes Prevention Program

Herman WH, Tyndall BD, Duru OK, Moin T, McEwen LN, Shao H, Ackermann RT, Jacobs SR, Neuwahl S, Kuo S, Zhang P, Pavkov ME, Villatoro[...]

Nardilysin in adipocyte regulates insulin sensitivity via HIF1alpha and PPARgamma

Matsuda S, Ohno M, Nishi K, Ikeda S, Iwasaki H, Eifuku T, Hiraoka Y, Kimura T, Ono K, Nishi E. Nardilysin in adipocyte regulates insulin[...]