PTPN22-CD45 dual phosphatase retrograde feedback enhances TCR signaling and autoimmunity

By afschroeder • September 6, 2025

Yang S, Santelli E, Gonzalez CG, Johnson WT, Choi IV, Zhuang C, Ro M, Rossitto LM, Yu IS, Lin SW, Zhan Y, Chen Q, Yoshihara JD, Wallace DJ, Jefferies CA, Yamashita M, Gonzalez DJ, Ainsworth RI, Shah NJ, Stanford SM, Bottini N. PTPN22-CD45 dual phosphatase retrograde feedback enhances TCR signaling and autoimmunity. Sci Adv. 2025 Sep 5;11(36):eadw2568. doi: 10.1126/sciadv.adw2568. Epub 2025 Sep 5. PMID: 40911684; PMCID: PMC12412669.

Tags: Cedars Sinai DoM, Publications, Rheumatology

Integrating Natural Language Processing With ChatGPT to Improve Quality of Artificial Intelligence Summaries of Prostate Cancer Consultations

Friedrich NA, Das SK, Luu M, Daniels JP, Heard J, Barsegyan A, Freedland SJ, Spiegel B, Kokorowski PK, Gonzalez Hernandez G, Daskivich TJ. Integrating Natural[...]

Clinical Triage of Individuals With Warning Symptoms of Imminent Cardiac Arrest

Reinier K, Chugh H, Kadiyala V, Sargsyan A, Uy-Evanado A, Nakamura K, Heckard E, Mathias M, Grogan T, Elashoff D, Salvucci A, Jui J, Chugh[...]

Comparing incidence of heart failure in individuals with enlarged cardiac chambers versus diabetes

Mirjalili SR, Atlas K, Reeves AP, Zhang C, Wasserthal J, Azimi A, Hashemi A, Mozafarybazargany M, Ghaffari Jolfayi A, Atlas T, Henschke CI, Yankelevitz DF,[...]