Distinct roles for NF-κB in hematopoietic stem cells and the bone marrow milieu in promoting hematopoietic aging

By afschroeder • August 29, 2025

Chia JJ, Singh A, Lin YS, Popko N, Mastro D, Liu Y, Tran T, King JK, Rao DS, Hoffmann A. Distinct roles for NF-κB in hematopoietic stem cells and the bone marrow milieu in promoting hematopoietic aging. Cell Rep. 2025 Aug 26;44(9):116193. doi: 10.1016/j.celrep.2025.116193. Epub ahead of print. PMID: 40875292.

Tags: bone marrow cytokine milieu, bone marrow niche, C/EBP, CP: Immunology, CP: Stem cell research, hematopoietic aging, hematopoietic stem cell impairment, Inflammaging, microenvironment, myeloid bias, NF-κB, Publications, Rheumatology, stem cell aging

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