FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity

By afschroeder • August 14, 2025

Panzitt K, Jungwirth E, Vosko LE, Madreiter-Sokolowski CT, Madl T, Tawfik I, Habisch H, Krstic J, Prokesch A, Karitnig R, Sucher R, Erdogan CY, Vallim TA, Trauner M, Fickert P, Al-Dury S, Molinaro A, Moore DD, Thallinger GG, Marschall HU, Wagner M. FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity. Sci Transl Med. 2025 Aug 13;17(811):eadn4558. doi: 10.1126/scitranslmed.adn4558. Epub 2025 Aug 13. PMID: 40802742.

Tags: Cardiology/Epi, Publications

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