FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity

By afschroeder • August 14, 2025

Panzitt K, Jungwirth E, Vosko LE, Madreiter-Sokolowski CT, Madl T, Tawfik I, Habisch H, Krstic J, Prokesch A, Karitnig R, Sucher R, Erdogan CY, Vallim TA, Trauner M, Fickert P, Al-Dury S, Molinaro A, Moore DD, Thallinger GG, Marschall HU, Wagner M. FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity. Sci Transl Med. 2025 Aug 13;17(811):eadn4558. doi: 10.1126/scitranslmed.adn4558. Epub 2025 Aug 13. PMID: 40802742.

Tags: Cardiology/Epi, Publications

Related Posts

Cardiovascular Imaging Considerations for Masters-Aged Athletes

Phelan DM, Claessen G, Eijsvogels TMH, Churchill TW, Dineen EH, Gati S, Guseh JS 2nd, Hsu JJ, Shah AB, Sperry BW, Wasfy MM, La Gerche[...]

Prognostic Value of AI-Based Quantitative Coronary CTA vs Human Reader-Based Visual Assessment: Results From the CONFIRM2 Registry

van Rosendael A, Nakanishi R, Bax JJ, Pontone G, Mushtaq S, Buechel RR, Gräni C, Feuchtner G, Lacaita PG, Patel AR, Singulane CC, Choi AD,[...]

Obesity mortality on the rise: A 54-year US perspective

Aamir J, Afridi MK, Sajid M, Khan TM, Qureshi S, Ahmed R, Fonarow GC, Minhas AMK, Waqas SA. Obesity mortality on the rise: A 54-year[...]