FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity

By afschroeder • August 14, 2025

Panzitt K, Jungwirth E, Vosko LE, Madreiter-Sokolowski CT, Madl T, Tawfik I, Habisch H, Krstic J, Prokesch A, Karitnig R, Sucher R, Erdogan CY, Vallim TA, Trauner M, Fickert P, Al-Dury S, Molinaro A, Moore DD, Thallinger GG, Marschall HU, Wagner M. FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity. Sci Transl Med. 2025 Aug 13;17(811):eadn4558. doi: 10.1126/scitranslmed.adn4558. Epub 2025 Aug 13. PMID: 40802742.

Tags: Cardiology/Epi, Publications

Peak Oxygen Uptake Prediction From Resting and Submaximal Variables of Cardiopulmonary Exercise Testing

Lee Y, Feng J, Rahrooh A, Bui AAT, Cooper CB, Hsu JJ. Peak Oxygen Uptake Prediction From Resting and Submaximal Variables of Cardiopulmonary Exercise Testing.[...]

Biologic Rescue With Tocilizumab: A Case of Refractory Chronic Pericardial Effusion in Systemic Sclerosis

Delgadillo R, Roufeh E, Lavelle B, Nguyen K, de la Rosa A. Biologic Rescue With Tocilizumab: A Case of Refractory Chronic Pericardial Effusion in Systemic[...]

A contemporary review on heart failure with improved ejection fraction

Weiss A, Flowers A, Eisenberg SD, Wu L, Rodriguez M, Khawaja M, Moras E, Lavie CJ, Fonarow GC, Tang WHW, Bozkurt B, Krittanawong C. A[...]