Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential

By afschroeder • August 6, 2025

Mercado-Gómez M, Goikoetxea-Usandizaga N, Giné AE, Merlos Rodrigo MA, Afonso MB, Azkargorta M, Zapata-Pavas LE, Rejano-Gordillo CM, Romero MR, Mendizabal I, Rodrigues PM, Wu H, Rodríguez-Agudo R, Serrano-Maciá M, Olaizola P, Barrenechea-Barrenechea JA, González Recio I, G Fernandez-Barrena M, Overi D, Gaudio E, Schaeper U, Garcia-Longarte S, Yáñez-Bartolomé M, Peña-SanFelix P, Gil-Pitarch C, Lapitz A, Michalkova H, Heger Z, Conter C, Macias RIR, Carracedo A, Bañales J, Moreno V, Lamarca A, Singh R, Delgado TC, Martínez-Cruz LA, Elortza F, Avila MA, Martín C, Tian TV, Macarulla T, Buccella D, Cubero FJ, Calvisi DF, Carpino G, Marin JJG, Rodrigues CMP, Martinez-Chantar ML. Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential. Gut. 2025 Aug 5:gutjnl-2024-333255. doi: 10.1136/gutjnl-2024-333255. Epub ahead of print. PMID: 40764063.

Tags: Cholangiocarcinoma, Digestive Diseases, Gene therapy, iron metabolism, Publications, reactive oxygen species

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