Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice

By afschroeder • August 3, 2025

Sendo S, Vela AJ, Ro M, Thiruppathy D, Wilkinson EL, Zhao Z, Hsieh WC, Yang S, Coras R, Bergot AS, Guma M, Nguyen A, McBride DA, Devkota S, Thomas R, Shah NJ, Svensson MND, Zengler K, Stanford SM, Bottini N. Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice. J Autoimmun. 2025 Jul 31;156:103452. doi: 10.1016/j.jaut.2025.103452. Epub ahead of print. PMID: 40752380.

Tags: Cedars Sinai DoM, Digestive Diseases, Publications, Rheumatology

The evolving role of ctDNA in colorectal cancer: guidance of adjuvant therapy or surveillance strategies?

Barrett LG, Gangi A, Hendifar A, Osipov A, Atkins K, Zaghiyan K, Nasseri Y, Murrell Z, Waters K, Mehta P, Zell JA, Hitchins MP, Gong[...]

Timing of Hypertensive Disorders of Pregnancy in Nulliparous Individuals and Risk of Incident Chronic Hypertension 2-7 Years Postpartum

Hauspurg A, Grobman W, Jancsura MK, Yee LM, Waks A, Simhan H, Levine LD, Theilen L, Greenland P, McNeil R, Bairey Merz CN, Shahrokni N,[...]

Response

Geft D, Matusov Y, Kolaitis N, DesJardin J, Barnett C, Hage A, De Marco T, Lewis MI. Response. Chest. 2026 Feb;169(2):e80-e81. doi: 10.1016/j.chest.2025.11.028. PMID: 41672669.